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Afobazol Anti Stress Tablets 10mg №60 (Afobazole)

Afobazol Anti Stress Tablets 10mg №60 (Afobazole)

Product Code: tablets
In Stock
Price: $19.99

Afobazol - a modern drug, developed by Russian scientists and pharmacologists.

Afobazol - the original drug, which has a specific mechanism of action. Therefore Afobazol not like other anti-anxiety and sedative drugs. Unlike most traditional drugs for the treatment of anxiety, Afobazol has no inhibitory effect on the central nervous system and is able to restore the natural mechanism that allows the nervous system to cope with stressful workloads.

Life is boring without stress. Agree, positive and negative emotions make life colorful and diverse in all its manifestations. Of course, if it moderately ...

But if you start to notice that you have the feeling of anxiety when you are constantly internally tense, feel baseless excitement - all of this can be the symptoms of "excessive", "pathological" alarm.

The problem is that we often feel a sense of inner tension a normal part of modern life. And try to cope with this state accessible and familiar ways - alcohol, athletic exercises, shopping, dive into the work ... It helps, but only for a while, besides often turns into addiction.

Anxiety condition, especially if it continues for a long time, significantly reduces quality of life. But the main thing - anxiety and tension can cause the development of diseases.

Therefore, it is important to remember that high state of anxiety and nervous tension is not the norm and requires appropriate treatment.

Modern anti-anxiety drug Afobazol allows to reduce or eliminate these symptoms of anxiety and nervous tension:

  • anxiety,
  • disturbing thoughts,
  • concerns
  • a premonition of trouble,
  • inability to relax,
  • nervousness,
  • irritability,
  • irrational fear,
  • sleep disorders.

including somatic symptoms of anxiety - in the form of infringements of work:

  • Cardiovascular system
  • Respiratory,
  • stomach and intestine.

vegetative disorders:

  • dizziness,
  • dry mouth,
  • sweating.

cognitive disorders:

  • difficulty in concentrating,
  • memory impairment.

Afobazol does not cause drowsiness or impairs attention, so ideally suited:

  • For the young, active people;
  • For modern business women and men;
  • For those whose profession is connected with the need to maintain a high concentration (for example, drivers and others.);
  • For anyone who wants to maintain their way of life.

Dosage Form:

  • Tablet

Composition per tablet:

  • Active ingredient: fabomotizol (fabomotizol dihydrochloride) - 5 mg and 10 mg.
  • Excipients: potato starch - 48 mg, microcrystalline cellulose - 40 mg (for 5 mg dosing) and 35 mg (for 10 mg dosing), lactose monohydrate - 48.5 mg, middle molecular povidone (medical middle molecular polyvinyl), Kollidon 25 - 7 mg, magnesium stearate - 1.5 mg.
  • Description: Tablets white or white with Valium a color shade, flat cylindrical with beveled.

Pharmacotherapeutic group:

  • Antianxiety drug (tranquilizer).


Afobazol® - selective non-benzodiazepine anxiolytic.

By acting on the sigma-1 receptors in the nerve cells of the brain, Afobazol® stabilizes GABA / benzodiazepine receptors and restores their sensitivity to endogenous mediators of inhibition. Afobazol® also increases bio-energy potential of nerve cells and protects them from damage (providing neuroprotection).

Action of the drug realized mainly in the form of a combination of anxiolytic (antianxiety) and light stimulus (activating) effects. Afobazol® reduces or eliminates anxiety (concern foreboding, fear, irritability), tension (fearfulness, tearfulness, anxiety, inability to relax, insomnia, fear), anxiety, somatic symptoms (muscle, sensory, cardiovascular, respiratory, gastrointestinal -kishechnye symptoms), vegetative disorders (dry mouth, sweating, dizziness), cognitive disorders (difficulty concentrating, impaired memory). Especially shows the application of the drug in patients with predominantly asthenic personality traits as disturbing suspiciousness, insecurity, increased vulnerability and emotional lability, tendency to emotional and stress reactions.

Effect of the drug develops on 5-7 day of treatment. The maximum effect is achieved by the end of 4 weeks of treatment and persists after the end of treatment an average of 1-2 weeks.

Afobazol® does not cause muscle weakness, drowsiness and has no negative influence on the concentration and memory. At its application is not formed and drug dependence does not develop the syndrome of "cancellation".


After oral administration Afobazol® well and rapidly absorbed from the gastrointestinal tract.

Maximum plasma concentrations (Cmax) - 0,130 + 0,073 mcg / ml; time to maximum concentration (Tmax) - 0.85 + 0.13 h.

Metabolism: Afobazol® exposed "first pass effect" through the liver, the main areas of metabolism are hydroxylation of the aromatic ring of the benzimidazole cycle of oxidation and morpholino moiety.

Afobazol® extensively distributed to well-vascularized organs, for it characterized fast transfer from the central pool (plasma) in the peripheral (highly vascularized organs and tissues).

The half-life of Afobazol® when taken orally 0.82 + 0.54 hours. The short half-life caused by intense biotransformation of the drug and rapid distribution from the blood plasma into the organs and tissues.

Indications for use:

Afobazol® used in adults with anxiety:

  • generalized anxiety disorder,
  • neurasthenia,
  • adjustment disorder,
  • in patients with various medical conditions (asthma, irritable bowel syndrome, systemic lupus erythematosus, ischemic heart disease, hypertension, arrhythmias),
  • dermatological, oncological, and others diseases.
  • In the treatment of sleep disorders associated with anxiety, neurocirculatory dystonia, premenstrual syndrome, alcohol withdrawal,
  • to facilitate syndrome of "cancel" for smoking cessation.

Dosage and administration:

  • Applied inside after eating.
  • The optimal single dose - 10 mg; DSA - 30 mg, distributed into 3 doses throughout the day. The duration of a course of the drug is - 2-4 weeks.
  • If necessary, on the recommendation of a doctor, the daily dose can be increased to 60 mg, and the duration of the treatment up to 3 months.

Side effects:

  • Allergic reactions are possible.
  • Rarely - headache, which usually resolves on its own and does not require discontinuation of therapy.


  • At a large overdose and intoxication may develop sedative effect and increased sleepiness without manifestations of muscle relaxation. As emergency care applied caffeine 20% solution in vials of 1.0 ml 2-3 times a day subcutaneously.

Effects on ability to drive vehicles, mechanisms:

  • The drug has no negative effect on driving and performance of potentially hazardous activities which require high concentration and speed of psychomotor reactions.

Interaction with other drugs:

  • Afobazol® does not react with ethanol and has no effect on the hypnotic effect of thiopental. It enhances the anticonvulsant effect of carbamazepine. Causes increased of anxiolytic action of diazepam.

Storage conditions:

  • Store at temperatures not above 25 ° C.
  • Keep out of the reach of children.

Shelf life:

  • 3 years. Do not use beyond the expiration date printed on the package.

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