Afobazol - a modern drug, developed by Russian scientists and pharmacologists.
Afobazol - the original drug, which has a specific mechanism of action. Therefore Afobazol not like other anti-anxiety and sedative drugs. Unlike most traditional drugs for the treatment of anxiety, Afobazol has no inhibitory effect on the central nervous system and is able to restore the natural mechanism that allows the nervous system to cope with stressful workloads.
Life is boring without stress. Agree, positive and negative emotions make life colorful and diverse in all its manifestations. Of course, if it moderately ...
But if you start to notice that you have the feeling of anxiety when you are constantly internally tense, feel baseless excitement - all of this can be the symptoms of "excessive", "pathological" alarm.
The problem is that we often feel a sense of inner tension a normal part of modern life. And try to cope with this state accessible and familiar ways - alcohol, athletic exercises, shopping, dive into the work ... It helps, but only for a while, besides often turns into addiction.
Anxiety condition, especially if it continues for a long time, significantly reduces quality of life. But the main thing - anxiety and tension can cause the development of diseases.
Therefore, it is important to remember that high state of anxiety and nervous tension is not the norm and requires appropriate treatment.
Modern anti-anxiety drug Afobazol allows to reduce or eliminate these symptoms of anxiety and nervous tension:
including somatic symptoms of anxiety - in the form of infringements of work:
Afobazol does not cause drowsiness or impairs attention, so ideally suited:
Composition per tablet:
Afobazol® - selective non-benzodiazepine anxiolytic.
By acting on the sigma-1 receptors in the nerve cells of the brain, Afobazol® stabilizes GABA / benzodiazepine receptors and restores their sensitivity to endogenous mediators of inhibition. Afobazol® also increases bio-energy potential of nerve cells and protects them from damage (providing neuroprotection).
Action of the drug realized mainly in the form of a combination of anxiolytic (antianxiety) and light stimulus (activating) effects. Afobazol® reduces or eliminates anxiety (concern foreboding, fear, irritability), tension (fearfulness, tearfulness, anxiety, inability to relax, insomnia, fear), anxiety, somatic symptoms (muscle, sensory, cardiovascular, respiratory, gastrointestinal -kishechnye symptoms), vegetative disorders (dry mouth, sweating, dizziness), cognitive disorders (difficulty concentrating, impaired memory). Especially shows the application of the drug in patients with predominantly asthenic personality traits as disturbing suspiciousness, insecurity, increased vulnerability and emotional lability, tendency to emotional and stress reactions.
Effect of the drug develops on 5-7 day of treatment. The maximum effect is achieved by the end of 4 weeks of treatment and persists after the end of treatment an average of 1-2 weeks.
Afobazol® does not cause muscle weakness, drowsiness and has no negative influence on the concentration and memory. At its application is not formed and drug dependence does not develop the syndrome of "cancellation".
After oral administration Afobazol® well and rapidly absorbed from the gastrointestinal tract.
Maximum plasma concentrations (Cmax) - 0,130 + 0,073 mcg / ml; time to maximum concentration (Tmax) - 0.85 + 0.13 h.
Metabolism: Afobazol® exposed "first pass effect" through the liver, the main areas of metabolism are hydroxylation of the aromatic ring of the benzimidazole cycle of oxidation and morpholino moiety.
Afobazol® extensively distributed to well-vascularized organs, for it characterized fast transfer from the central pool (plasma) in the peripheral (highly vascularized organs and tissues).
The half-life of Afobazol® when taken orally 0.82 + 0.54 hours. The short half-life caused by intense biotransformation of the drug and rapid distribution from the blood plasma into the organs and tissues.
Indications for use:
Afobazol® used in adults with anxiety:
Dosage and administration:
Effects on ability to drive vehicles, mechanisms:
Interaction with other drugs: